Human Atrial Fibrillation Is Not Associated With Remodeling of Ryanodine Receptor Clusters

The release of Ca(2+) by ryanodine receptor (RyR2) channels is critical for cardiac function. However, abnormal RyR2 activity has been linked to the development of arrhythmias, including increased spontaneous Ca(2+) release in human atrial fibrillation (AF). Clustering properties of RyR2 have been s...

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Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Munro, Michelle L., van Hout, Isabelle, Aitken-Buck, Hamish M., Sugunesegran, Ramanen, Bhagwat, Krishna, Davis, Philip J., Lamberts, Regis R., Coffey, Sean, Soeller, Christian, Jones, Peter P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947344/
https://ncbi.nlm.nih.gov/pubmed/33718369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.633704
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