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Curcumin Acts as a Positive Allosteric Modulator of α(7)-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain
Effects of curcumin, a major ingredient of turmeric, were tested on the function of the α(7)-subunit of the human nicotinic acetylcholine (α(7)-nACh) receptor expressed in Xenopus oocytes and on nociception in mouse models of tonic and visceral pain. Curcumin caused a significant potentiation of cur...
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| Publicado no: | J Pharmacol Exp Ther |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7947331/ https://ncbi.nlm.nih.gov/pubmed/29339457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.245068 |
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