TNFRSF1B Gene Variants and Related Soluble TNFR2 Levels Impact Resilience in Alzheimer's Disease

Tumor necrosis factor receptor 2 (TNFR2) promotes neuronal survival downstream. This longitudinal study evaluated whether the TNFRSF1B gene encoding TNFR2 and levels of its soluble form (sTNFR2) affect Alzheimer disease (AD) biomarkers and clinical outcomes. Data analyzed included 188 patients in th...

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Bibliografiske detaljer
Udgivet i:Front Aging Neurosci
Main Authors: Pillai, Jagan A., Bebek, Gurkan, Khrestian, Maria, Bena, James, Bergmann, Cornelia C., Bush, William S., Leverenz, James B., Bekris, Lynn M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947258/
https://ncbi.nlm.nih.gov/pubmed/33716716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.638922
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