TNFRSF1B Gene Variants and Related Soluble TNFR2 Levels Impact Resilience in Alzheimer's Disease

Tumor necrosis factor receptor 2 (TNFR2) promotes neuronal survival downstream. This longitudinal study evaluated whether the TNFRSF1B gene encoding TNFR2 and levels of its soluble form (sTNFR2) affect Alzheimer disease (AD) biomarkers and clinical outcomes. Data analyzed included 188 patients in th...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Pillai, Jagan A., Bebek, Gurkan, Khrestian, Maria, Bena, James, Bergmann, Cornelia C., Bush, William S., Leverenz, James B., Bekris, Lynn M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947258/
https://ncbi.nlm.nih.gov/pubmed/33716716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.638922
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