Induction of Therapeutic Protection in an HPV16-Associated Mouse Tumor Model Through Targeting the Human Papillomavirus-16 E5 Protein to Dendritic Cells

HPV E5 is an oncoprotein mainly expressed in premalignant lesions, which makes it an important target for a vaccine to prevent or cure cervical cancer (CC). In this study, we evaluated whether E5 targeted to DEC-205, present in dendritic cells (DCs), could induce a therapeutic protection against HPV...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Badillo-Godinez, Oscar, Pedroza-Saavedra, Adolfo, Valverde-Garduño, Veronica, Bermudez-Morales, Victor, Maldonado-Gama, Minerva, Leon-Letelier, Ricardo, Bonifaz, Laura C., Esquivel-Guadarrama, Fernando, Gutierrez-Xicotencatl, Lourdes
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947241/
https://ncbi.nlm.nih.gov/pubmed/33717073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.593161
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados