Case Report: Reversible Neurotoxicity and a Clinical Response Induced by BCMA-Directed Chimeric Antigen Receptor T Cells Against Multiple Myeloma With Central Nervous System Involvement

Isolated central nervous system involvement in multiple myeloma (CNS-MM) is rare and carries extremely poor prognosis. Chimeric antigen receptor T cell therapy (CART) targeting B-cell maturation antigen (BCMA) is demonstrated as a promising strategy in MM treatment, but the clinical safety and effic...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zhang, Ying, Zhang, Changfeng, Zhou, Jin, Zhang, Jingren, Chen, Xiaochen, Chen, Jia, Wang, Pu, Sun, Xiuli, Lou, Xiaoyan, Qi, Wei, Kang, Liqing, Yu, Lei, Wu, Depei, Li, Caixia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947195/
https://ncbi.nlm.nih.gov/pubmed/33717057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.552429
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