Inflammation Modulation by Vitamin D and Calcium in the Morphologically Normal Colorectal Mucosa of Colorectal Adenoma Patients in a Clinical Trial

Increased cyclooxygenase-2 (COX-2) and decreased 15-hydroxyprostaglandin dehydrogenase (15-HPGD) expression promote prostaglandin-mediated inflammation and colorectal carcinogenesis. Experimental studies suggest that vitamin D and calcium may inhibit these pathways, but their effects on colorectal t...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Gibbs, David Corley, Fedirko, Veronika, Baron, John A., Barry, Elizabeth L., Flanders, W. Dana, McCullough, Marjorie L., Yacoub, Rami, Raavi, Tapasya, Rutherford, Robin E., Seabrook, March E., Bostick, Roberd M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947029/
https://ncbi.nlm.nih.gov/pubmed/32917645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-20-0140
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