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Effects of supplemental vitamin D and calcium on markers of proliferation, differentiation, and apoptosis in the normal colorectal mucosa of colorectal adenoma patients

To clarify the roles of vitamin D and calcium as potential chemopreventive agents against colorectal cancer in humans, and to develop “treatable”, pre-neoplastic, phenotypic biomarkers of risk for colorectal neoplasms, we estimated the effects of supplemental vitamin D(3) (1,000 IU/day [25 μg/day])...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gao, Yasheen, Um, Caroline Y., Fedirko, Veronika, Rutherford, Robin E., Seabrook, March E., Barry, Elizabeth L., Baron, John A., Bostick, Roberd M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296527/
https://ncbi.nlm.nih.gov/pubmed/30557404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208762
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