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Deletion of Mea6 in Cerebellar Granule Cells Impairs Synaptic Development and Motor Performance

The cerebellum is conceptualized as a processor of complex movements. Many diseases with gene-targeted mutations, including Fahr’s disease associated with the loss-of-function mutation of meningioma expressed antigen 6 (Mea6), exhibit cerebellar malformations, and abnormal motor behaviors. We previo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Dev Biol
Prif Awduron: Wang, Xin-Tai, Zhou, Lin, Cai, Xin-Yu, Xu, Fang-Xiao, Xu, Zhi-Heng, Li, Xiang-Yao, Shen, Ying
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946997/
https://ncbi.nlm.nih.gov/pubmed/33718348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.627146
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