TRAF6 Regulates the Immunosuppressive Effects of Myeloid-Derived Suppressor Cells in Tumor-Bearing Host

Myeloid-derived suppressor cells (MDSCs) are immature heterogeneous cells derived from the bone marrow and they are the major component of the tumor-induced immunosuppressive environment. Tumor necrosis factor receptor-associated factor 6 (TRAF6), an E3 ubiquitin ligase, catalyzes the polyubiquitina...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Song, Ge, Zhang, Yue, Tian, Jie, Ma, Jie, Yin, Kai, Xu, Huaxi, Wang, Shengjun
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946975/
https://ncbi.nlm.nih.gov/pubmed/33717204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.649020
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