Long Non-Coding RNA HOXA Transcript Antisense RNA Myeloid-Specific 1–HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung Cancer

HOXA transcript antisense RNA myeloid-specific 1 (HOTAIRM1) is a long non-coding RNA that has been shown to be a key regulator of myeloid cell development by targeting HOXA1. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that possess immunosuppress...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Tian, Xinyu, Ma, Jie, Wang, Ting, Tian, Jie, Zhang, Yue, Mao, Lingxiang, Xu, Huaxi, Wang, Shengjun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890118/
https://ncbi.nlm.nih.gov/pubmed/29662483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00473
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