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Epigenome wide association study of response to methotrexate in early rheumatoid arthritis patients

AIM: To identify differentially methylated positions (DMPs) and regions (DMRs) that predict response to Methotrexate (MTX) in early rheumatoid arthritis (RA) patients. MATERIALS AND METHODS: DNA from baseline peripheral blood mononuclear cells was extracted from 72 RA patients. DNA methylation, quan...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gosselt, Helen R., Vallerga, Costanza L., Mandaviya, Pooja R., Lubberts, Erik, Hazes, Johanna M. W., de Jonge, Robert, Heil, Sandra G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946177/
https://ncbi.nlm.nih.gov/pubmed/33690661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247709
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