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Chemoenzymatic route to stereodefined 2-(azidophenyl)oxazolines for click chemistry

Aryl-substituted esters of a racemic diprotected 2-azido-1-alkanol were submitted to the Staudinger/aza-Wittig reaction in order to assess scope and establish conditions for their cyclization to the corresponding 2,4,5-trisubstituted oxazolines. Following the cyclization study, the (2R,3R)-antipode...

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Publicat a:Tetrahedron Lett
Autors principals: Monsen, Paige J., Luzzio, Frederick A.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946107/
https://ncbi.nlm.nih.gov/pubmed/33716327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2020.152717
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