The development of novel cytochrome P450 2J2 (CYP2J2) inhibitor and the underlying interaction between inhibitor and CYP2J2

Human Cytochrome P450 2J2 (CYP2J2) as an important metabolic enzyme, plays a crucial role in metabolism of polyunsaturated fatty acids (PUFAs). Elevated levels of CYP2J2 have been associated with various types of cancer, and therefore it serves as a potential drug target. Herein, using a high-throug...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Tian, Xiangge, Zhou, Meirong, Ning, Jing, Deng, Xiaopeng, Feng, Lei, Huang, Huilian, Yao, Dahong, Ma, Xiaochi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946002/
https://ncbi.nlm.nih.gov/pubmed/33682565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1896500
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