Exosomal miR-409-3p secreted from activated mast cells promotes microglial migration, activation and neuroinflammation by targeting Nr4a2 to activate the NF-κB pathway

OBJECTIVE: Neuroinflammation plays a critical role in central nervous system diseases. Exosomal miRNAs released from various cells are implicated in cell-to-cell communication. Prior studies have placed substantial emphasis on the role of cytokines in mast cell-microglia interactions during neuroinf...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Hu, Liuqing, Si, Linjie, Dai, Xiaonan, Dong, Hongquan, Ma, Zijian, Sun, Zhaochu, Li, Nana, Sha, Huanhuan, Chen, Yinan, Qian, Yanning, Zhang, Zhiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7945321/
https://ncbi.nlm.nih.gov/pubmed/33750404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02110-5
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