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Activated brain mast cells contribute to postoperative cognitive dysfunction by evoking microglia activation and neuronal apoptosis

BACKGROUND: Neuroinflammation plays a key role in the occurrence and development of postoperative cognitive dysfunction (POCD). Microglia, the resident immune cells in the brain, has been increasingly recognized to contribute to neuroinflammation. Although brain mast cells (MCs) are the “first respo...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Zhang, Xiang, Dong, Hongquan, Li, Nana, Zhang, Susu, Sun, Jie, Zhang, Shu, Qian, Yanning
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888609/
https://ncbi.nlm.nih.gov/pubmed/27245661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0592-9
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