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Activated brain mast cells contribute to postoperative cognitive dysfunction by evoking microglia activation and neuronal apoptosis

BACKGROUND: Neuroinflammation plays a key role in the occurrence and development of postoperative cognitive dysfunction (POCD). Microglia, the resident immune cells in the brain, has been increasingly recognized to contribute to neuroinflammation. Although brain mast cells (MCs) are the “first respo...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Zhang, Xiang, Dong, Hongquan, Li, Nana, Zhang, Susu, Sun, Jie, Zhang, Shu, Qian, Yanning
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888609/
https://ncbi.nlm.nih.gov/pubmed/27245661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0592-9
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