Effects of N-Linked Glycan on Lassa Virus Envelope Glycoprotein Cleavage, Infectivity, and Immune Response

Lassa virus (LASV) belongs to the Mammarenavirus genus (family Arenaviridae) and causes severe hemorrhagic fever in humans. The glycoprotein complex (GPC) contains eleven N-linked glycans that play essential roles in GPC functionalities such as cleavage, transport, receptor recognition, epitope shie...

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Vydáno v:Virol Sin
Hlavní autoři: Zhu, Xueqin, Liu, Yang, Guo, Jiao, Cao, Junyuan, Wang, Zonglin, Xiao, Gengfu, Wang, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Singapore 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7945000/
https://ncbi.nlm.nih.gov/pubmed/33689141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-021-00358-y
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