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mTOR inhibitor INK128 promotes wound healing by regulating MDSCs

BACKGROUND: Skin wounds in diabetic patients hardly recover. Accumulating evidence has shown that mammalian target of rapamycin (mTOR) pathway and myeloid-derived suppressor cells (MDSCs) are involved in inflammatory-related response. INK128 is a novel mTOR kinase inhibitor in clinical development....

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Li, Yi, Xu, Yujun, Liu, Xinhan, Yan, Xin, Lin, Yue, Tan, Qian, Hou, Yayi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944919/
https://ncbi.nlm.nih.gov/pubmed/33691762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02206-y
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