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Antagonism between antiviral signaling and glycolysis
RLR-mediated interferon production is critical for antiviral responses. A recent study (Zhang et al., Cell 2019;178: 176–189) uncovered a reciprocal inhibition between RLR signaling and glycolysis: lactate produced by glycolysis inhibits RLR signaling by binding to RLR signaling component MAVS, wher...
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| Gepubliceerd in: | Trends Endocrinol Metab |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7944876/ https://ncbi.nlm.nih.gov/pubmed/31349923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2019.07.010 |
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