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Airway exposure to perfluorooctanoate exacerbates airway hyperresponsiveness and downregulates glucocorticoid receptor expression in asthmatic mice

BACKGROUND: Multiple environmental risk factors play a vital role in the pathogenesis of asthma, which contribute to the phenotypic expression of asthma. Perfluorooctanoate (PFOA) is the most common and abundant perfluorocarbon (PFC) in humans, and it has been detected in water and the atmosphere wo...

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Bibliographic Details
Published in:Transl Pediatr
Main Authors: Zeng, Zeyu, Ma, Weihui, Zhao, Ran, Dong, Xiaoyan
Format: Artigo
Language:Inglês
Published: AME Publishing Company 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944165/
https://ncbi.nlm.nih.gov/pubmed/33708518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tp-20-246
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