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Airway exposure to perfluorooctanoate exacerbates airway hyperresponsiveness and downregulates glucocorticoid receptor expression in asthmatic mice

BACKGROUND: Multiple environmental risk factors play a vital role in the pathogenesis of asthma, which contribute to the phenotypic expression of asthma. Perfluorooctanoate (PFOA) is the most common and abundant perfluorocarbon (PFC) in humans, and it has been detected in water and the atmosphere wo...

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Detalhes bibliográficos
Publicado no:Transl Pediatr
Main Authors: Zeng, Zeyu, Ma, Weihui, Zhao, Ran, Dong, Xiaoyan
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944165/
https://ncbi.nlm.nih.gov/pubmed/33708518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tp-20-246
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