Failure of Glial Cell-Line Derived Neurotrophic Factor (GDNF) in Clinical Trials Orchestrated By Reduced NR4A2 (NURR1) Transcription Factor in Parkinson’s Disease. A Systematic Review

Parkinson’s disease (PD) is one of the most common neurodegenerative maladies with unforeseen complex pathologies. While this neurodegenerative disorder’s neuropathology is reasonably well known, its etiology remains a mystery, making it challenging to aim therapy. Glial cell-line derived neurotroph...

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Vydáno v:Front Aging Neurosci
Hlavní autoři: Kambey, Piniel Alphayo, Kanwore, Kouminin, Ayanlaja, Abiola Abdulrahman, Nadeem, Iqra, Du, YinZhen, Buberwa, Wokuheleza, Liu, WenYa, Gao, Dianshuai
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943926/
https://ncbi.nlm.nih.gov/pubmed/33716718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.645583
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