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The NTCP p.Ser267Phe Variant Is Associated With a Faster Anti-HBV Effect on First-Line Nucleos(t)ide Analog Treatment

Sodium taurocholate cotransporting polypeptide (NTCP) acts as a cellular receptor for the hepatitis B virus infection of host hepatocytes. Previously, many studies confirmed that the NTCP p.Ser267Phe variant was a protective factor against HBV-related disease progression. We therefore designed this...

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Publicat a:Front Pharmacol
Autors principals: Wu, Lina, Xu, Wenxiong, Li, Xuejun, Liu, Ying, Wang, Lu, Zhu, Shu, Yang, Fangji, Xie, Chan, Peng, Liang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943921/
https://ncbi.nlm.nih.gov/pubmed/33716744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.616858
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