Diverse Effects of the NTCP p.Ser267Phe Variant on Disease Progression During Chronic HBV Infection and on HBV preS1 Variability

The sodium taurocholate co-transporting polypeptide (NTCP) acts as a cellular receptor for the hepatitis B virus (HBV) infection on host hepatocytes. We aim to investigate how the NTCP p.Ser267Phe variant affects HBV-related disease progression and analyze viral genomic variability under a host gene...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Infect Microbiol
Hauptverfasser: Yang, Fangji, Wu, Lina, Xu, Wenxiong, Liu, Ying, Zhen, Limin, Ning, Gang, Song, Jie, Jiao, Qian, Zheng, Yongyuan, Chen, Tongtong, Xie, Chan, Peng, Liang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Cellular and Infection Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407604/
https://ncbi.nlm.nih.gov/pubmed/30881922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00018
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