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RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2

Growing evidences suggest that cancer stem cells exhibit many molecular characteristics and phenotypes similar to their ancestral progenitor cells. In the present study, human embryonic stem cells are induced to differentiate into hepatocytes along hepatic lineages to mimic liver development in vitr...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Wang, Xia, Wang, Jin, Tsui, Yu-Man, Shi, Chaoran, Wang, Ying, Zhang, Xin, Yan, Qian, Chen, Miao, Jiang, Chen, Yuan, Yun-Fei, Wong, Chun-Ming, Liu, Ming, Feng, Zeng-yu, Chen, Honglin, Ng, Irene Oi Lin, Jiang, Lingxi, Guan, Xin-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943813/
https://ncbi.nlm.nih.gov/pubmed/33750796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21828-7
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