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Generation and characterization of CD19-iCre mice as a tool for efficient and specific conditional gene targeting in B cells
The Cre/loxP system is a powerful tool for generating conditional gene knockout (KO) mice and elucidate gene function in vivo. CD19-Cre and Mb1-iCre transgenic mice are commonly used for generating B cell-specific KO mice and investigate the development, as well as the physiological and pathophysiol...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7943778/ https://ncbi.nlm.nih.gov/pubmed/33750849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84786-6 |
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