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hCD2-iCre and Vav-iCre Mediated Gene Recombination Patterns in Murine Hematopoietic Cells

Cre-recombinase mediated conditional deletion of Lox-P site flanked ("floxed") genes is widely used for functional gene annotation in mice. Many different Cre-transgenic mouse lines have been developed for cell-type specific gene disruption. But often, the precise tissue-patterns of Cre ac...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Siegemund, Sabine, Shepherd, Jovan, Xiao, Changchun, Sauer, Karsten
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401753/
https://ncbi.nlm.nih.gov/pubmed/25884630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124661
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