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Structural resolution of switchable states of a de novo peptide assembly
De novo protein design is advancing rapidly. However, most designs are for single states. Here we report a de novo designed peptide that forms multiple α-helical-bundle states that are accessible and interconvertible under the same conditions. Usually in such designs amphipathic α helices associate...
Shranjeno v:
| izdano v: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7943578/ https://ncbi.nlm.nih.gov/pubmed/33750792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21851-8 |
| Oznake: |
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