Genome-wide analysis of DNA methylation in Hirschsprung enteric precursor cells: unraveling the epigenetic landscape of enteric nervous system development

BACKGROUND: Hirschsprung disease (HSCR, OMIM 142623) is a rare congenital disorder that results from a failure to fully colonize the gut by enteric precursor cells (EPCs) derived from the neural crest. Such incomplete gut colonization is due to alterations in EPCs proliferation, survival, migration...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Villalba-Benito, Leticia, López-López, Daniel, Torroglosa, Ana, Casimiro-Soriguer, Carlos S., Luzón-Toro, Berta, Fernández, Raquel María, Moya-Jiménez, María José, Antiñolo, Guillermo, Dopazo, Joaquín, Borrego, Salud
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7942176/
https://ncbi.nlm.nih.gov/pubmed/33750457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01040-6
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