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Overexpression of DNMT3b target genes during Enteric Nervous System development contribute to the onset of Hirschsprung disease
Hirschsprung disease (HSCR) is attributed to a failure of neural crest cells (NCCs) to migrate, proliferate, differentiate and/or survive in the bowel wall during embryonic Enteric Nervous System (ENS) development. ENS formation is the result from a specific gene expression pattern regulated by epig...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5524929/ https://ncbi.nlm.nih.gov/pubmed/28740121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06539-8 |
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