Association with CYP2C19 polymorphisms and Clopidogrel in treatment of elderly stroke patients

BACKGROUND: Clopidogrel is an antiplatelet drug used in the treatment of ischemic stroke. Safety and efficacy of clopidogrel has been confirmed in CAPRIE, PRoFESS trials. However, these studies focused on patients aged less than 75 years. CYP2C19 polymorphisms resulted in individual differences in c...

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Udgivet i:BMC Neurol
Main Authors: Li, Changqing, Jia, Weihua, Li, Jian, Li, Fangfei, Ma, Jing, Zhou, Lichun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941922/
https://ncbi.nlm.nih.gov/pubmed/33685396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-021-02127-6
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