Pyridoxal-5′-phosphate-dependent enzyme GenB3 Catalyzes C-3′,4′-dideoxygenation in gentamicin biosynthesis

Eitemau Tebyg

• The bifunctional enzyme, GenB4, catalyzes the last step of gentamicin 3′,4′-di-deoxygenation via reduction and transamination activities
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  Cyhoeddwyd: (2020)
• Pyridoxal-5′-phosphate–dependent bifunctional enzyme catalyzed biosynthesis of indolizidine alkaloids in fungi
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  Cyhoeddwyd: (2020)
• Similarity between pyridoxal/pyridoxamine phosphate-dependent enzymes involved in dideoxy and deoxyaminosugar biosynthesis and other pyridoxal phosphate enzymes.
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  Cyhoeddwyd: (1994)
• The GenK-catalyzed C-6′ Methylation in the Biosynthesis of Gentamicin: Isolation and Characterization of a Cobalamin-dependent Radical SAM Enzyme
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  Cyhoeddwyd: (2013)
• Conformation and reaction specificity in pyridoxal phosphate enzymes.
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  Cyhoeddwyd: (1966)