Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

Established in vitro models for SARS-CoV-2 infection are limited and include cell lines of non-human origin and those engineered to overexpress ACE2, the cognate host cell receptor. We identified human H522 lung adenocarcinoma cells as naturally permissive to SARS-CoV-2 infection despite complete ab...

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Foilsithe in:bioRxiv
Main Authors: Puray-Chavez, Maritza, LaPak, Kyle M., Schrank, Travis P., Elliott, Jennifer L., Bhatt, Dhaval P., Agajanian, Megan J., Jasuja, Ria, Lawson, Dana Q., Davis, Keanu, Rothlauf, Paul W., Jo, Heejoon, Lee, Nakyung, Tenneti, Kasyap, Eschbach, Jenna E., Mugisha, Christian Shema, Vuong, Hung R., Bailey, Adam L., Hayes, D. Neil, Whelan, Sean P.J., Horani, Amjad, Brody, Steven L., Goldfarb, Dennis, Major, M. Ben, Kutluay, Sebla B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory 2021
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941617/
https://ncbi.nlm.nih.gov/pubmed/33688646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.03.01.433431
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