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The Effects of Repeat-Dose Doxorubicin on Cardiovascular Functional Endpoints and Biomarkers in the Telemetry-Equipped Cynomolgus Monkey

Purpose: Doxorubicin-related heart failure has been recognized as a serious complication of cancer chemotherapy. This paper describes a cardiovascular safety pharmacology study with chronic dosing of doxorubicin in a non-human primate model designed to characterize the onset and magnitude of left ve...

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Bibliografiske detaljer
Udgivet i:Front Cardiovasc Med
Main Authors: Engwall, Michael J., Everds, Nancy, Turk, James R., Vargas, Hugo M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941602/
https://ncbi.nlm.nih.gov/pubmed/33708802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2021.587149
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