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Novel approaches for glioblastoma treatment: Focus on tumor heterogeneity, treatment resistance, and computational tools

BACKGROUND: Glioblastoma (GBM) is a highly aggressive primary brain tumor. Currently, the suggested line of action is the surgical resection followed by radiotherapy and treatment with the adjuvant temozolomide, a DNA alkylating agent. However, the ability of tumor cells to deeply infiltrate the sur...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Rep (Hoboken)
Hauptverfasser: Valdebenito, Silvana, D'Amico, Daniela, Eugenin, Eliseo
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941428/
https://ncbi.nlm.nih.gov/pubmed/32729241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cnr2.1220
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