Sensory neurons derived from diabetic rats exhibit deficits in functional glycolysis and ATP that are ameliorated by IGF-1

OBJECTIVE: The distal dying-back of the longest nerve fibres is a hallmark of diabetic neuropathy, and impaired provision of energy in the form of adenosine triphosphate (ATP) may contribute to this neurodegenerative process. We hypothesised that energy supplementation via glycolysis and/or mitochon...

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Bibliografiska uppgifter
I publikationen:Mol Metab
Huvudupphovsmän: Aghanoori, Mohamad-Reza, Margulets, Vicky, Smith, Darrell R., Kirshenbaum, Lorrie A., Gitler, Daniel, Fernyhough, Paul
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2021
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940986/
https://ncbi.nlm.nih.gov/pubmed/33592336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101191
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