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Designed whole-cell-catalysis-assisted synthesis of 9,11-secosterols

A method for the synthesis of 9,11-secosteroids starting from the natural corticosteroid cortisol is described. There are two key steps in this approach, combining chemistry and synthetic biology. Stereo- and regioselective hydroxylation at C9 (steroid numbering) is carried out using whole-cell bioc...

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Detaylı Bibliyografya
Yayımlandı:Beilstein J Org Chem
Asıl Yazarlar: Kõllo, Marek, Kasari, Marje, Kasari, Villu, Pehk, Tõnis, Järving, Ivar, Lopp, Margus, Jõers, Arvi, Kanger, Tõnis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Beilstein-Institut 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940815/
https://ncbi.nlm.nih.gov/pubmed/33747232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.17.52
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