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Elevated Brain Glutamate Levels in Bipolar Disorder and Pyruvate Carboxylase-Mediated Anaplerosis

In vivo (1)H magnetic resonance spectroscopy studies have found elevated brain glutamate or glutamate + glutamine levels in bipolar disorder with surprisingly high reproducibility. We propose that the elevated glutamate levels in bipolar disorder can be explained by increased pyruvate carboxylase-me...

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Bibliografiske detaljer
Udgivet i:Front Psychiatry
Main Authors: Shen, Jun, Tomar, Jyoti Singh
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940766/
https://ncbi.nlm.nih.gov/pubmed/33708149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2021.640977
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