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Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro

Perineuronal nets (PNNs) are specialized, reticular structures of the extracellular matrix (ECM) that can be found covering the soma and proximal dendrites of a neuronal subpopulation. Recent studies have shown that PNNs can highly influence synaptic plasticity and are disrupted in different neurops...

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Detalhes bibliográficos
Publicado no:Front Synaptic Neurosci
Main Authors: Wegrzyn, David, Freund, Nadja, Faissner, Andreas, Juckel, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940526/
https://ncbi.nlm.nih.gov/pubmed/33708102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2021.637549
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