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Poly I:C Activated Microglia Disrupt Perineuronal Nets and Modulate Synaptic Balance in Primary Hippocampal Neurons in vitro

Perineuronal nets (PNNs) are specialized, reticular structures of the extracellular matrix (ECM) that can be found covering the soma and proximal dendrites of a neuronal subpopulation. Recent studies have shown that PNNs can highly influence synaptic plasticity and are disrupted in different neurops...

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Bibliografische gegevens
Gepubliceerd in:Front Synaptic Neurosci
Hoofdauteurs: Wegrzyn, David, Freund, Nadja, Faissner, Andreas, Juckel, Georg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940526/
https://ncbi.nlm.nih.gov/pubmed/33708102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2021.637549
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