Primary Hippocampal Neurons, Which Lack Four Crucial Extracellular Matrix Molecules, Display Abnormalities of Synaptic Structure and Function and Severe Deficits in Perineuronal Net Formation

The extracellular matrix (ECM) of the brain plays crucial roles during the development, maturation, and regeneration of the CNS. In a subpopulation of neurons, the ECM condenses to superstructures called perineuronal nets (PNNs) that surround synapses. Camillo Golgi described PNNs a century ago, yet...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Geissler, Maren, Gottschling, Christine, Aguado, Ainhara, Rauch, Uwe, Wetzel, Christian H., Hatt, Hanns, Faissner, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618965/
https://ncbi.nlm.nih.gov/pubmed/23637166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3275-12.2013
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