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Primary Hippocampal Neurons, Which Lack Four Crucial Extracellular Matrix Molecules, Display Abnormalities of Synaptic Structure and Function and Severe Deficits in Perineuronal Net Formation

The extracellular matrix (ECM) of the brain plays crucial roles during the development, maturation, and regeneration of the CNS. In a subpopulation of neurons, the ECM condenses to superstructures called perineuronal nets (PNNs) that surround synapses. Camillo Golgi described PNNs a century ago, yet...

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Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Geissler, Maren, Gottschling, Christine, Aguado, Ainhara, Rauch, Uwe, Wetzel, Christian H., Hatt, Hanns, Faissner, Andreas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618965/
https://ncbi.nlm.nih.gov/pubmed/23637166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3275-12.2013
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