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Neurodegeneration Upon Dysfunction of Endosomal/Lysosomal CLC Chloride Transporters

The regulation of luminal ion concentrations is critical for the function of, and transport between intracellular organelles. The importance of the acidic pH in the compartments of the endosomal-lysosomal pathway has been well-known for decades. Besides the V-ATPase, which pumps protons into their l...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Bose, Shroddha, He, Hailan, Stauber, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940362/
https://ncbi.nlm.nih.gov/pubmed/33708769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.639231
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