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Cyclic Guanosine Monophosphate–Adenosine Monophosphate Synthase (cGAS), a Multifaceted Platform of Intracellular DNA Sensing

Innate immune pathways are the first line of cellular defense against pathogen infections ranging from bacteria to Metazoa. These pathways are activated following the recognition of pathogen associated molecular patterns (PAMPs) by membrane and cytosolic pattern recognition receptors. In addition, s...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Verrier, Eloi R., Langevin, Christelle
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940176/
https://ncbi.nlm.nih.gov/pubmed/33708225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.637399
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