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Cyclic Guanosine Monophosphate–Adenosine Monophosphate Synthase (cGAS), a Multifaceted Platform of Intracellular DNA Sensing

Innate immune pathways are the first line of cellular defense against pathogen infections ranging from bacteria to Metazoa. These pathways are activated following the recognition of pathogen associated molecular patterns (PAMPs) by membrane and cytosolic pattern recognition receptors. In addition, s...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Verrier, Eloi R., Langevin, Christelle
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940176/
https://ncbi.nlm.nih.gov/pubmed/33708225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.637399
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