Identification of guanine nucleotide exchange factors that increase Cdc42 activity in primary human endothelial cells

The Rho GTPase family is involved in actin dynamics and regulates the barrier function of the endothelium. One of the main barrier-promoting Rho GTPases is Cdc42, also known as cell division control protein 42 homolog. Currently, regulation of Cdc42-based signalling networks in endothelial cells (EC...

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Publicat a:Small GTPases
Autors principals: Reinhard, Nathalie R., Van Der Niet, Sanne, Chertkova, Anna, Postma, Marten, Hordijk, Peter L., Gadella Jr., Theodorus W.J., Goedhart, Joachim
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939571/
https://ncbi.nlm.nih.gov/pubmed/31469028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2019.1658509
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