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LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior

Lamins form stable filaments at the nuclear periphery in metazoans. Unlike B-type lamins, lamins A and C localize also in the nuclear interior, where they interact with lamin-associated polypeptide 2 alpha (LAP2α). Using antibody labeling, we previously observed a depletion of nucleoplasmic A-type l...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Naetar, Nana, Georgiou, Konstantina, Knapp, Christian, Bronshtein, Irena, Zier, Elisabeth, Fichtinger, Petra, Dechat, Thomas, Garini, Yuval, Foisner, Roland
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939549/
https://ncbi.nlm.nih.gov/pubmed/33605210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63476
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