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A kinetic dissection of the fast and superprocessive kinesin-3 KIF1A reveals a predominant one-head-bound state during its chemomechanical cycle

The kinesin-3 family contains the fastest and most processive motors of the three neuronal transport kinesin families, yet the sequence of states and rates of kinetic transitions that comprise the chemomechanical cycle and give rise to their unique properties are poorly understood. We used stopped-f...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zaniewski, Taylor M., Gicking, Allison M., Fricks, John, Hancock, William O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939386/
https://ncbi.nlm.nih.gov/pubmed/33082143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014961
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