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Adenylate kinase AK2 isoform integral in embryo and adult heart homeostasis
Adenylate kinase 2 (AK2) catalyzes trans-compartmental nucleotide exchange, but the functional implications of this mitochondrial intermembrane isoform is only partially understood. Here, transgenic AK2−/− null homozygosity was lethal early in embryo, indicating a mandatory role for intact AK2 in ut...
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| Udgivet i: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7939106/ https://ncbi.nlm.nih.gov/pubmed/33571905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.01.097 |
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