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Adenylate kinase AK2 isoform integral in embryo and adult heart homeostasis

Adenylate kinase 2 (AK2) catalyzes trans-compartmental nucleotide exchange, but the functional implications of this mitochondrial intermembrane isoform is only partially understood. Here, transgenic AK2−/− null homozygosity was lethal early in embryo, indicating a mandatory role for intact AK2 in ut...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochem Biophys Res Commun
Prif Awduron: Zhang, Song, Yamada, Satsuki, Park, Sungjo, Klepinin, Aleksandr, Kaambre, Tuuli, Terzic, Andre, Dzeja, Petras
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939106/
https://ncbi.nlm.nih.gov/pubmed/33571905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.01.097
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