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Cardiac troponin-I phosphorylation underlies myocardial contractile dysfunction induced by hypothermia rewarming
Rewarming the intact heart after a period of hypothermia is associated with reduced myocardial contractility, decreased Ca(2+) sensitivity, and increased cardiac troponin-I (cTnI) phosphorylation. We hypothesized that hypothermia/rewarming (H/R) induces left ventricular (LV) contractile dysfunction...
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| Pubblicato in: | Am J Physiol Heart Circ Physiol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7938809/ https://ncbi.nlm.nih.gov/pubmed/31373512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00101.2019 |
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