Cardiac troponin-I phosphorylation underlies myocardial contractile dysfunction induced by hypothermia rewarming

Rewarming the intact heart after a period of hypothermia is associated with reduced myocardial contractility, decreased Ca(2+) sensitivity, and increased cardiac troponin-I (cTnI) phosphorylation. We hypothesized that hypothermia/rewarming (H/R) induces left ventricular (LV) contractile dysfunction...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Heart Circ Physiol
Asıl Yazarlar: Tveita, Torkjel, Arteaga, Grace M., Han, Young-Soo, Sieck, Gary C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7938809/
https://ncbi.nlm.nih.gov/pubmed/31373512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00101.2019
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