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Hypothermia/rewarming disrupts excitation-contraction coupling in cardiomyocytes
Hypothermia/rewarming (H/R) is poorly tolerated by the myocardium; however, the underlying intracellular basis of H/R-induced cardiac dysfunction remains elusive. We hypothesized that in cardiomyocytes, H/R disrupts excitation-contraction coupling by reducing myofilament Ca(2+) sensitivity due to an...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935512/ https://ncbi.nlm.nih.gov/pubmed/26993227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00840.2015 |
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